Ursodeoxycholic Acid Market is Anticipated to Witness High Growth

Ursodeoxycholic acid, also known as ursodiol, is a bile acid produced by the liver that is used for treating liver diseases. The increasing prevalence of gallstones and liver diseases like primary sclerosing cholangitis and viral hepatitis is driving the demand for ursodeoxycholic acid. Ursodeoxycholic acid helps in dissolving, preventing, or reducing the formation of gallstones in the gallbladder and bile ducts. It also helps improve liver function and prevent graft failure in liver transplant patients.

Key Takeaways

Key players operating in the Ursodeoxycholic Acid market are Philips, GE Healthcare, Medtronic, Siemens Healthineers, Stryker, Abbott, Boston Scientific, Johnson & Johnson, Canon Medical Systems, Baxter. Ursodeoxycholic acid is primarily used for treating gallstone disease and liver diseases like primary sclerosing cholangitis. The increasing prevalence of these diseases across the globe is expected to drive the demand for UDCA significantly. North America accounts for the largest share in the global UDCA market owing to high awareness and healthcare expenditure in the region. However, Asia Pacific is expected to witness fastest growth over the forecast period owing to surging patient pool, improving healthcare infrastructure and economic conditions. Key players are focusing on expanding their presence in emerging markets of Asia Pacific and Latin America through acquisitions and collaborations to gain competitive advantage.

Market Drivers

Increasing prevalence of gallstones and liver diseases- The rising cases of gallstone diseases, viral hepatitis, and primary biliary cholangitis globally is a key factor driving the demand for ursodeoxycholic acid. UDCA lowers cholesterol concentration in bile and makes it less prone to stone formation.

Growing awareness about benefits of UDCA- There is increasing awareness among patients and healthcare professionals about the therapeutic benefits of UDCA in liver disease treatment. Initiatives by key players to educate people is also boosting the market growth.

Market Restraints

Side effects associated with long term use- Long term use of ursodeoxycholic acid has shown side effects like diarrhea and fatigue. This may discourage its use among some patients.

Availability of alternative treatment options- Other drugs like obeticholic acid have emerged as alternative options for liver diseases like primary biliary cholangitis with lesser side effects. This poses a threat to the UDCA market.

Segment Analysis

The Ursodeoxycholic Acid Market Size can be segmented based on grade as synthetic and natural. Among these, the synthetic grade segment holds a major market share owing to its lower price as compared to natural grade. Synthetic grade ursodeoxycholic acid is produced via chemical synthesis in the laboratories from natural bile acids using lithocholic acid as a starting material. The availability of synthetic grade ursodeoxycholic acid at lower prices has made it a preferred choice for use among consumers.

The market can also be segmented based on application as liver disease, gallstones, celiac disease, and others. Of these, the liver disease segment dominates the market due to growing prevalence of liver conditions like cirrhosis and hepatitis worldwide. Ursodeoxycholic acid effectively treats primary biliary cirrhosis and is approved by FDA for this indication. Its use for dissolving gallstones and treatment of celiac disease has also been increasing over the years.

Global Analysis 

The North America region accounts for a significant share in the global ursodeoxycholic acid market owing to developed healthcare infrastructure, high awareness levels about bile acid therapy, and expanding applications of ursodeoxycholic acid. The approval of ursodeoxycholic acid for various liver conditions by FDA along with availability of branded formulations of leading players have boosted the market growth in North America. Asia Pacific is poised to witness fastest growth in the upcoming years due to rising healthcare spending, growing prevalence of liver ailments, and increasing focus of international players in Asia Pacific markets.

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