The nanobodies market is growing at a rapid pace owing to their ability to enable superior resolution imaging. Nanobodies are recombinant single domain antibody fragments derived from camelids that have unique biophysical and biochemical properties advantageous for biotechnological and biomedical applications. Owing to their small size of only 15kDa, nanobodies can penetrate tissues and access epitopes that are cryptic for regular antibodies. Their strong binding affinity and specificity along with high stability and solubility makes them an ideal molecule for various biomedical applications including molecular imaging, targeted drug delivery and diagnosis of diseases.
The global nanobodies market is estimated to be valued at US$ 1447.48 Mn in 2024 and is expected to exhibit a CAGR of 4.5% over the forecast period 2024 to 2031.
Key Takeaways
Key players operating in the nanobodies market are 3M, Auto Custom Carpet Inc., Autotech Nonwovens Pvt Ltd., Conform Automotive, Feltex, GAHH LLC, RACEMARK International, LLC, Lloyd Mats Inc., German Auto Tops Inc., Lear Corporation (Masland Corporation), Low & Bonar PLC, Suminoe Textile Co., Ltd., Toyota Boshoku Corporation, Walser GmbH, MacNeil Automotive Products Limited (WeatherTech), Husky Liners, Inc. (Truck Hero, Inc.), and Lund International, Inc. The rising demand for targeted drug delivery and non-invasive diagnostic methods is fueling the growth of the nanobodies market. Nanobodies have enabled development of biosensors and molecular probes for in vivo tumor imaging with high sensitivity and specificity. Advancements in protein engineering and phage display techniques have augmented the production of recombinant nanobodies against various targets.
Market Trends
Personalized Medicine: Nanobodies can be employed for developing personalized medicines against cancer, neurological and infectious diseases by delivering drugs or imaging agents selectively to disease sites. This reduces toxicity and improves treatment efficacy.
Non-Invasive Diagnostics: Nanobodies facilitate non-invasive diagnostic procedures like PET, SPECT and MRI imaging for early detection of cancers and other disorders. They enable precise visualization of pathological regions for timely clinical intervention.
Market Opportunities
Neurological Disorders: Nanobodies hold promise for diagnosis and targeted therapy of neurological conditions like Alzheimer's, Parkinson's, epilepsy and stroke. R&D in this area can unlock new opportunities.
Infectious Diseases: Developing nanobody-based imaging probes and anti-viral therapies provides opportunities for combating global health threats posed by HIV/AIDS, influenza, antimicrobial resistance etc.
Impact of COVID-19 on Nanobodies Market growth
The COVID-19 pandemic has significantly impacted the growth of the global nanobodies market. During the initial phase of the pandemic, many countries imposed strict lockdowns causing disruptions in the supply chain and logistics. This reduced the consumption and demand for nanobodies which are used across various end-use industries such as healthcare, research, and diagnostics. However, COVID-19 also boosted the research activities to develop nanobody-based treatments and diagnostics for coronavirus. Many companies and research institutes started collaborating to accelerate the development of nanobody therapeutics against SARS-CoV-2. For instance, the Brains Bioceutical entered into an agreement with the University of Liège in Belgium to advance nanobody therapeutics for combating coronaviruses including COVID-19. Such initiatives have provided growth opportunities to the nanobodies market during the pandemic. Going forward, growing focus on development of novel diagnostics and therapeutics is likely to drive the market post-COVID period. Companies need to focus more on R&D to widen the scope of nanobody applications that address the evolving healthcare needs in the post-pandemic world.
Geographical regions with highest concentration in Nanobodies market
North America holds the largest share in the global nanobodies market in terms of value, followed by Europe. This is attributed to strong presence of key pharmaceutical and biotechnology companies engaged in nanobody research and development in these regions. For instance, companies such as Ablynx (a Sanofi company), MorphoSys, and Novimmune are developing various nanobody-based therapeutic candidates to treat diseases such as cancer and respiratory infections. Additionally, favorable government funding for antibody research along with availability of advanced technology infrastructure supports the growth of nanobodies market in North America and Europe. On the other hand, Asia Pacific is anticipated to be the fastest growing region during the forecast period due to increasing R&D investment by governments and private organizations in countries like China, India, and South Korea. Emergence of domestic players focusing on development of affordable nanobody-based therapies will further accelerate the market growth in Asia Pacific over the coming years.
Geographical region with fastest growth for Nanobodies market
Asia Pacific region is projected to witness the highest growth in the global nanobodies market during the forecast period. This is due to rising research and development activities supported by growing public and private investments in healthcare sector across countries like China, India, and South Korea. Growing awareness, increasing per capita healthcare expenditure, and expanding biopharmaceutical industry in Asia Pacific is attracting many global players to establish their base in this region to leverage huge market potential. Presence of large patient pool and rising demand for affordable therapeutics and diagnostics makes Asia Pacific a lucrative nanobody market. Additionally, government initiatives such as 'Make in India' encourages foreign investments to strengthen nanotechnology and biopharma industry. These factors are expected to fuel the demand for nanobodies from healthcare and research sectors, thereby fueling the market growth in Asia Pacific region in the near future.
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