Double Marker Test – Purpose, Procedure, Normal Range & Cost
At Redcliffe Labs, you can book the Double Marker Test with affordable pricing, free home sample collection, and NABL-certified accurate reports.

Pregnancy is a beautiful journey, but it also requires medical supervision to ensure the mother and baby are healthy. The Double Marker Test is one of the most important screenings during the first trimester to detect genetic abnormalities in the developing fetus.

At Redcliffe Labs, you can book the Double Marker Test with affordable pricing, free home sample collection, and NABL-certified accurate reports.

What is the Double Marker Test?

The Double Marker Test is a prenatal screening blood test usually conducted between the 11th and 14th week of pregnancy.

It measures two important substances in the mother’s blood:

  • Free Beta-hCG (Human Chorionic Gonadotropin): A pregnancy hormone.

  • PAPP-A (Pregnancy-Associated Plasma Protein A): A protein produced by the placenta.

Abnormal levels of these markers may indicate a higher risk of:

  • Down Syndrome (Trisomy 21)

  • Edwards Syndrome (Trisomy 18)

  • Patau Syndrome (Trisomy 13)

Why is the Double Marker Test Important?

  • Detects chromosomal abnormalities early in pregnancy.

  • Provides valuable information for better pregnancy management.

  • Helps parents make informed medical decisions.

  • Is non-invasive and completely safe for both mother and baby.

Who Should Take the Test?

While useful for all pregnant women, it is especially recommended for:

  • Women aged 35 years or older.

  • Expecting mothers with a family history of genetic disorders.

  • Women with a history of miscarriages or abnormal pregnancies.

  • Couples undergoing IVF or assisted conception.

Procedure of the Double Marker Test

  1. A blood sample is collected from the mother.

  2. Levels of Free Beta-hCG and PAPP-A are analyzed.

  3. Results are often combined with an NT (Nuchal Translucency) ultrasound scan for greater accuracy.

  4. Based on findings, the pregnancy is classified as low-risk or high-risk.

Normal Range

  • High Free Beta-hCG: May indicate Down syndrome.

  • Low Free Beta-hCG: May indicate Edwards or Patau syndrome.

  • Low PAPP-A: Associated with chromosomal abnormalities.

Since values differ by age, health, and gestational week, results should always be interpreted by a doctor.

Cost of Double Marker Test in India

The cost of the test generally ranges from ₹2,500 to ₹3,500.

At Redcliffe Labs, you benefit from:

  • Free home sample collection

  • Affordable test packages

  • NABL-accredited lab reports

  • Results within 24–48 hours

Conclusion

The Double Marker Test is a safe and essential screening during the first trimester that helps in the early detection of chromosomal abnormalities. While it does not confirm genetic conditions, it provides a strong basis for further diagnostic tests if required.

 

Book your Double Marker Test with Redcliffe Labs today and ensure a safe pregnancy journey with accurate reports and hassle-free home collection.

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