The advancement of pharmaceutical science heavily relies on the availability of high-quality chemical intermediates. One such essential intermediate is 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine, widely used in the synthesis of Tofacitinib, a well-known Janus kinase (JAK) inhibitor used to treat autoimmune diseases such as rheumatoid arthritis and psoriatic arthritis.
In this article, we’ll explore the significance of this compound in Tofacitinib synthesis and how Vidgastech is contributing to the global supply of premium-quality pharmaceutical intermediates.
🔬 What is 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine?
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a nitrogen-containing heterocyclic compound used as a building block in medicinal chemistry. With its reactive chloro group and fused ring structure, it plays a crucial role in the construction of complex drug molecules, especially in the synthesis of Tofacitinib, a third-generation targeted therapy.
💊 Role in Tofacitinib Synthesis
Tofacitinib targets the JAK-STAT signaling pathway, helping manage autoimmune inflammation. The synthesis of Tofacitinib involves multiple synthetic steps, and 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine acts as one of the core intermediates. It contributes to the pyrrolopyrimidine backbone in the final API (Active Pharmaceutical Ingredient).
Pharmaceutical manufacturers rely on this intermediate for consistent yield and purity during scale-up and formulation processes.
🏭 Vidgastech: Your Trusted Supplier of Tofacitinib Intermediates
Vidgastech specializes in the manufacturing and global distribution of high-quality pharmaceutical intermediates, including 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine. With a focus on quality, compliance, and customer satisfaction, Vidgastech has become a reliable partner for pharmaceutical companies, research labs, and CROs.
🌟 Why Choose Vidgastech?
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✅ High-purity intermediates suitable for pharmaceutical synthesis
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✅ Custom synthesis and bulk supply options
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✅ On-time global delivery with proper documentation
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✅ Stringent quality control and batch traceability
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✅ Technical and regulatory support from experienced chemists
🔍 Technical Details:
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Chemical Name: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
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Molecular Formula: C6H4ClN3
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Molecular Weight: 153.57 g/mol
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CAS Number: [Insert if applicable]
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Appearance: [White to light yellow solid or as per actual]
📦 Applications:
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Tofacitinib API synthesis
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JAK inhibitor research
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Medicinal chemistry building block
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Custom pharmaceutical R&D
📞 Contact Vidgastech
For inquiries, quotations, or bulk orders of 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine or other Tofacitinib intermediates, reach out to Vidgastech today.
🌐 Website: https://www.vidgastech.com
