Drug Discovery Services | Comprehensive Pharmaceutical Discovery Solutions
Piramal Pharma Solutions offers comprehensive drug discovery services, from synthetic chemistry to in-vitro biology and scalable solutions worldwide

Drug Discovery Services | Comprehensive Pharmaceutical Discovery Solutions

Laboratory for pharmaceutical research Drug Discovery Services

Piramal's Discovery Services (PDS) site in Ahmedabad, India, provide comprehensive drug discovery services, including synthetic chemistry, in-vitro biology, in-vitro ADME, route scouting, and non-GMP scale-up. We serve large and mid-sized pharma companies, biotech firms, and academic institutions worldwide. Since commencing operations in early 2003, we have focused on aiding start-ups and biotech companies, growing into a team of over 300 scientists working in world-class chemistry laboratories. PDS can provide forward integration with the company's drug substance and formulation sites in North America, UK & India, ensuring seamless support throughout the drug development lifecycle.

Featured Services

Synthetic Chemistry Laboratory Services Synthetic Chemistry Services for Drug Discovery

The specialized team at Piramal Discovery Solutions (PDS) makes it one of the most reputed synthetic chemistry services providers for mg to kg scale discovery chemistry requirements and boasts of a broader experience in preparing high quality small molecule NCEs. PDS is proficient in developing methodologies, including the synthesis of single, multi-step, small arrays as well as designing of focused libraries for use in hit-to-lead and lead optimization projects.&nbsp

Access to scientific literature and databases such as SciFinder and Reaxys enables the team to modify and develop novel synthetic routes. Compound delivery is accompanied with characterization data including high-field NMR, and mass and purity by LC-MS/HPLC/GC. Also, the Supercritical Fluid Chromatography aids chiral separation and generates a higher throughput.

Piramal's in vitro biology services are designed to provide best-in-class support for preclinical drug discovery. Our offerings include assay development, hit identification, hit-to-lead and lead optimization, incorporating HTS, multiplex assay development, primary/secondary functional assays, HCS, and selectivity studies. Our assay team can develop, and screen compounds, with miniaturization of assays achieved by using 96 and 384-well plates. Our assays are validated rigorously using tool compounds with QC established (signal: noise ratio Z'-prime uniformity reproducibility).

The in vitro facilities at Piramal Discovery Services, Ahmedabad, deliver comprehensive DMPK services, including absorption, distribution, metabolism, and excretion (ADME) solutions. These services support faster and more informed decision-making in drug discovery programs or as standalone offerings.&nbsp

Clients benefit from cost-efficient, standardized, and customized assays for assessing key ADME parameters, ensuring precise and reliable results tailored to their unique project requirements.

Our fully equipped kilo lab enables the rapid development of scalable and robust chemical processes using advanced methodologies. This capability is critical for ensuring quick supply during the early development phase and for evaluating the scalability of the original process.&nbsp

The analytical team collaborates closely with chemists, leading method development, preparative purification and characterization. This collaboration allows chemists to focus on troubleshooting, ensuring better efficiencies and faster deliveries.

Piramal Pharma has over 60 years of expertise in small molecule API development and manufacturing. Our global facilities are equipped to meet your drug substance needs, with dedicated development resources worldwide. As a reliable supply chain partner globally, we support your drug substance development goals.

We offer comprehensive support for custom API development services, covering Route Scouting, Pre-GMP Kilo Lab, Process Development, and Analytical Development, with expertise and flexibility.

We offer API manufacturing services at lab, kilo, and pilot scales, catering to preclinical studies, all stages of clinical trials, and commercialization, providing quantities ranging from milligrams to kilograms.

Piramal's Generic API division provides a diverse range of off-patent APIs tailored for global markets.

Piramal's Riverview facility offers High Potency API (HPAPI) services. Our teams are experts in the cGMP production of highly potent compounds, from grams to kilograms. With over 50 years of experience in manufacturing, handling, and containment of highly potent compounds, we prioritize safety and quality in all our operations.

Drug Discovery Services | Comprehensive Pharmaceutical Discovery Solutions
disclaimer

What's your reaction?

Comments

https://timessquarereporter.com/business/public/assets/images/user-avatar-s.jpg

0 comment

Write the first comment for this!

Facebook Conversations