Liver cirrhosis refers to scarring (fibrosis) of the liver tissue and poor functioning of the liver. It is caused by excessive alcohol consumption over many years or due to chronic hepatitis virus infections such as hepatitis B or C. The progression of fibrosis leads to nodule formation and ultimately to cirrhosis. The key symptoms of liver cirrhosis include jaundice, fatigue, abdominal pain, weakness, loss of appetite, nausea and vomiting. Treatment for liver cirrhosis depends on the severity of the disease and includes medications to improve liver functions, antibiotics to treat infections, diuretics to remove excess fluid and sometimes orthotopic liver transplantation.
The Liver Cirrhosis Market is estimated to be valued at US$ 1.41 Bn in 2024 and is expected to exhibit a CAGR of 5.2% over the forecast period 2024-2031.
Key Takeaways
Key players operating in the liver cirrhosis market are Madrigal Pharmaceuticals, Inc., Galectin Therapeutics Inc., Grifols Therapeutics LLC, Cyma Bay Therapeutics, Akero Therapeutics, Inc.
Key players operating in the liver cirrhosis market are increasingly investing in R&D to develop advanced treatment options. For instance, Madrigal Pharmaceuticals is developing resmetirom, a first-in-class thyroid hormone receptor beta-selective agonist for the treatment of non-alcoholic steatohepatitis (NASH) and liver cirrhosis.
The growing prevalence of excessive alcohol consumption and obesity are major factors fueling the demand for liver cirrhosis treatment solutions. According to WHO, around 3 million deaths each year result from harmful use of alcohol. Excessive alcohol intake damages liver cells making the organ less able to regenerate, leading to the development of cirrhosis over the years.
Technological advancements in liver transplantation techniques coupled with the emergence of effective post-transplant medications have increased the eligibility of patients and survival rates post transplantation. Shortage of liver donors however remains a key challenge. Companies are investing in development of artificial or bio-engineered livers as potential alternatives.
Market Trends
Increasing Adoption Of Targeted Therapies: Pharma companies are focusing on developing targeted therapies for liver cirrhosis that specifically act on certain molecular targets or pathways involved in disease progression. For example, Galectin Therapeutics' drug belapectin blocks galectin-3 activity involved in fibrotic response and necrosis.
Rise Of Combination Therapies: Due to multifactorial nature of the disease, companies are exploring efficacy of combining two or more treatment modalities for synergistic effects. For example, combination of antiviral medications with immunomodulators to achieve sustained virologic response.
Market Opportunities
Asia Pacific presents high growth prospects owing to changing lifestyles, abusive consumption of alcohol and growing obesity rates. Public-private partnerships can help facilitate more affordable healthcare access in emerging economies.
Emergence of non-invasive diagnostic tools leveraging imaging and biomarkers hold potential to precisely diagnose and monitor disease progression and treatment response without need for repeated liver biopsies. This can increase patient acceptance and compliance.
Impact Of COVID-19 On Liver Cirrhosis Market Growth
The COVID-19 pandemic has significantly impacted the growth of the liver cirrhosis market. During the initial phases of the pandemic, factors like lockdowns, restrictions on non-essential medical services led to postponement of diagnosis procedures and delay in treatment. This adversely impacted the market growth initially. However, as the healthcare sector learned to cope and adapt to the new normal, telehealth services gained prominence helping maintain continuity of care virtually. With the development and availability of vaccines as well, the market is recovering fast. However, challenges like availability of medical staff, hospital beds, and potential risks of severe COVID infection in cirrhosis patients still persist and need to be addressed. The immediate focus post pandemic is to boost diagnosis and treatment rates back to pre-COVID levels. Intensifying awareness campaigns and policies promoting community healthcare can aid in early detection and management of cirrhosis cases.
Geographical Regions With Highest Liver Cirrhosis Market Value
North America dominates the Liver Cirrhosis Market in terms of value. The region accounted for over 35% market share in 2024 owing to rising prevalence of cirrhosis caused by non-alcoholic steatohepatitis (NASH) and alcohol abuse. Growing healthcare spending and availability of advanced treatment options have further augmented the regional market. Europe ranks second with major markets being Germany, United Kingdom, France and Italy. Developed healthcare infrastructure, supportive reimbursement environment and presence of key industry players have boosted the European market.
Fastest Growing Region For Liver Cirrhosis Market
Asia Pacific is identified as the fastest growing regional market for liver cirrhosis expected to expand at a CAGR of around 7% during the forecast years. Growing consumption of alcohol, rising obesity rates attributed to changing lifestyles and dietary habits have majorly contributed to increased cirrhosis burden in the region. Countries like China, India and Japan have emerged as high potential markets. Rapid economic development, rising healthcare expenditure, growing medical tourism are some factors favoring the Asia Pacific liver cirrhosis market. Initiatives to spread awareness about lifestyle-related liver diseases can further augment the regional market opportunities.
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Author Bio:
Alice Mutum is a seasoned senior content editor at Coherent Market Insights, leveraging extensive expertise gained from her previous role as a content writer. With seven years in content development, Alice masterfully employs SEO best practices and cutting-edge digital marketing strategies to craft high-ranking, impactful content. As an editor, she meticulously ensures flawless grammar and punctuation, precise data accuracy, and perfect alignment with audience needs in every research report. Alice's dedication to excellence and her strategic approach to content make her an invaluable asset in the world of market insights. (LinkedIn: www.linkedin.com/in/alice-mutum-3b247b137 )
What Are The Key Data Covered In This Liver Cirrhosis Market Report?
:- Market CAGR throughout the predicted period
:- Comprehensive information on the aspects that will drive the Liver Cirrhosis Market's growth between 2024 and 2031.
:- Accurate calculation of the size of the Liver Cirrhosis Market and its contribution to the market, with emphasis on the parent market
:- Realistic forecasts of future trends and changes in consumer behaviour
:- Liver Cirrhosis Market Industry Growth in North America, APAC, Europe, South America, the Middle East, and Africa
:- A complete examination of the market's competitive landscape, as well as extensive information on vendors
:- Detailed examination of the factors that will impede the expansion of Liver Cirrhosis Market vendors
FAQ’s
Q.1 What are the main factors influencing the Liver Cirrhosis Market?
Q.2 Which companies are the major sources in this industry?
Q.3 What are the market’s opportunities, risks, and general structure?
Q.4 Which of the top Liver Cirrhosis Market companies compare in terms of sales, revenue, and prices?
Q.5 Which businesses serve as the Liver Cirrhosis Market’s distributors, traders, and dealers?
Q.6 How are market types and applications and deals, revenue, and value explored?
Q.7 What does a business area’s assessment of agreements, income, and value implicate?
*Note:
1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it
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