Antisense Oligonucleotides Market is Anticipated to Witness High Growth

Antisense oligonucleotides are short synthetic strands of nucleic acid, designed to bind specifically to their complementary RNA strands through Watson-Crick base pairing. They can be used to modify gene expression by neutralizing sense nucleic acids. The increasing adoption of personalized medicines along with the ability of antisense oligonucleotides to treat various genetic diseases is driving the growth of this market. These oligonucleotides are being used for treatment of neuromuscular diseases, cancer, and genetic disorders.

Key Takeaways

Key players operating in the antisense oligonucleotides market are SICK AG, Hitachi Ltd., Honeywell International Inc., Hyundai Elevator Co. Ltd., Nidec MCE, Toshiba Elevators and Building Systems, Thames Valley Controls, and Mitsubishi Electric. These companies are developing innovative antisense oligonucleotides drugs and technology platforms for processing oligonucleotides.

The major opportunities in the antisense oligonucleotides market include their potential use in treating various genetic disorders like spinal muscular atrophy (SMA), Huntington's disease etc. Many biotech and pharmaceutical companies are exploring clinical applications of antisense oligonucleotides which will further drive the market growth.

Globally, North America dominates the antisense oligonucleotides market due to increasing research activities for developing personalized medicines. However, Asia Pacific region is expected to exhibit fastest growth owing to rising cases of chronic diseases, growing awareness regarding advanced treatment options and improving healthcare infrastructure. Major players are also looking to establish their manufacturing and research facilities in Asia Pacific and Latin American countries to leverage low-cost opportunities.

Market drivers:

The key driver for Antisense Oligonucleotides Market Size is increasing prevalence of genetic disorders globally. As per some estimates, over 6000 rare diseases has been identified with majority having genetic origins. Further, rising geriatric population susceptible to chronic diseases like cancer is also driving the need for effective targeted treatments delivered through antisense oligonucleotides.

Market restrain: High development cost of antisense oligonucleotides drugs is a major challenge hampering the market growth. Developing an antisense oligonucleotide drug requires extensive research and clinical trials to study safety, efficacy and delivery mechanisms. This pushes the overall cost of drug development making it difficult for small companies to develop and commercialize antisense oligonucleotides.

Segment Analysis

The antisense oligonucleotides market can be segmented by technology, indication, and region. The RNA-targeting segment is dominating currently as RNA oligonucleotides provide greater knockdown effect and better target specificity, compared to DNA oligonucleotides. They are more commonly used for neuromuscular diseases, cancer, and genetic disorders, where silencing of a gene expression is required. Among indications, cancer is the most prominent sub-segment currently due to growing need to treat or manage different types of cancer. Research is ongoing to develop oligonucleotides that can target various cancer-causing genes and receptors.

Global Analysis

Regionally, North America holds the largest share in the antisense oligonucleotides market owing to technological advancement in biotechnology, rising healthcare investment, and increasing R&D activities for the treatment of genetic disorders. The Asia Pacific region is expected to grow at the fastest rate during the forecast period due to rising cancer prevalence, improving healthcare infrastructure, and increasing spending on drug research. The rapidly growing geriatric population also drives the demand for advanced treatment options. Additionally, favorable government policies to support drug development will boost growth in emerging countries of Asia andLatin America.

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